Key publications

Tiet MY, … Hensiek AE, Horvath R: Biomarkers in Ataxia Telangiectasia – a systematic Review. J Neurol 2024, in press

Tiet MY, … Hensiek AE: A novel biomarker for Ataxia Telangiectasia: Evaluating the lack of hypointensity of the dentate nuclei. JNNP 2024, in press

Major T, … Hensiek AE: Validation of the ataxia telangiectasia neurological examination scale toolkit (AT-NEST) for use in adults with ataxia telangiectasia. Cerebellum 2024, 23 (2); 455-458

Lam T, .., Hensiek A, ..Tucci A: Repeat expansions in NOP56 are a cause of spinocerebellar ataxia type 36 in the British population, Brain Commun. 2023 ;5(5):fcad244

Wilson A, Hensiek AE, Jones, M, Scoffings D. Labrune syndrome and pregnancy : case report. Obstetric medicine 2023, in press

Tiet M, Nannoni S, Scoffings D, Horvath R, Markus HM, Hensiek AE: White matter hyperintensities and cerebral microbleeds in Ataxia Telangiectasia. Neurology Gemnetics 2021;7(6): e640

Nakornchai T, Conci E, Hensiek, AE, Brown JWKL. Clinician and patient experience of neurology telephone consultations during the COVID-19 pandemic. Postgrad Med J 2021:141234-41

Tiet M, Horvath R, Hensiek AE: Ataxia Telangiectasia – what the neurologist needs to know. Pract Neurol 2020, 20(5):404-414

Teng M, Horvath R, Hensiek A: Ataxia Telangiectasia – what the neurologist needs to know. Pract Neurol 2020, in press

Schon K, van Os N, Oscroft N, Baxendale H, Scoffings D, Ray J, Suri M, Whitehouse WP, Mehta PR, Everett N, Bottolo L, van de Warrenburg BP, Byrd PJ, Weemaes C, Willemsen MA, Tischkowitz M, Taylor AM, Hensiek AE. : Genotype, extrapyramidal features and severity of variant Ataxia-Telangiectasia. Ann Neurol. 2019, 85(2):170-180

van Os NJH, Hensiek A, van Gaalen J, Taylor AMR, van Deuren M, Weemaes CMR, Willemsen MAAP, van de Warrenburg BPC. Trajectories of motor abnormalities in milder phenotypes of ataxia telangiectasia.Neurology. 2019 Jan 1;92:e19-e29

Morris, KA, Afridi, S, Evans G , Hensiek A, Kellet, M, Halliday D, Pretorius P, Parry A: The response of spinal cord Ependymomas to Bevacizumab in patients with Neurofibromatosis type 2. J Neurosurg Spine. 2016 Dec 16:1-9

Hensiek AE, Taylor AMR: The clinical variability of Ataxia Telangiectasia – an update. ACNR 2015; 15(2): 8- 12

Hensiek A, Kirker S, Evan E: Diagnosis, investigation and management of hereditary spastic paraplegia in the era of next generation sequencing. J Neurol 2015; 262 (7): 1601 – 12

Tysome JR, Macfarlane R, Durie-Gair J, Donnelly N, Mannion R, Knight R, Harris F, Vanat ZH, Tam YC, Burton K, Hensiek A, Raymond FL, Moffat DA, Axon PR. Surgical management of vestibular schwannomas and hearing rehabilitation in neurofibromatosis type 2. Otol Neurotol. 2012 Apr;33(3):466-72

Hensiek AE, Seaman SR, Barcellos L, Oturai A, Eraksoi M, Cocco E, Vecsei L, Steward G, Dubois B, Bellman-Strobl J, Leone M, Anderson O, Bencsik K, Booth D, Celius EG, Harbo H, Hauser S, Heard R, Hillert J, Myhr KM, Marrosu MG, Oksenberg J, Rajda C, Sawcer SJ, Soelberg Sørensen P, Zipp F, Compston DAS. Familial effects on the clinical course of multiple sclerosis. Neurology 2007, 30;68(5):376-83

Hensiek AE, Absalom T: Status epilepticus. Anaestheasia and Intensive Care medicine 2006. 7 (4); 127 – 128

Vera J, Hensiek A, Woodrow C, Crawley F, Krishna S: Ophthalmoplegia and slurred speech in an intravenous drug user, PLoS Medicine 2006, 3(12):e453

The Games Collaborative Group, Ban M, Booth D, Heard R, Stewart G, Goris A, Vandenbroeck K, Dubois B, Laaksonen M, Ilonen J, Alizadeh M, Edan G, Babron MC, Brassat D, Clanet M, Cournu-Rebeix I, Fontaine B, Semana G, Goedde R, Epplen J, Weber A, Infante-Duarte C, Zipp F, Rajda C, Bencsik K, Vécsei L, Heggarty S, Graham C, Hawkins S, Liguori M, Momigliano-Richiardi P, Caputo D, Grimaldi LM, Leone M, Massacesi L, Milanese C, Salvetti M, Savettieri G, Trojano M, Bielecki B, Mycko MP, Selmaj K, Santos M, Maciel P, Pereira C, Silva A, Silva BM, Coraddu F, Marrosu MG, Akesson E, Hillert J, Datta P, Oturai A, Harbo HF, Spurkland A, Goertsches R, Villoslada P, Eraksoy M, Hensiek A, Compston A, Setakis E, Gray J, Yeo TW, Sawcer : Linkage disequilibrium screening for multiple sclerosis implicates JAG1 and POU2AF1 as susceptibility genes in Europeans, J Neuroimmunol. 2006 Oct;179(1-2):108-16.

Roxburgh RH, Sawcer S, Maranian M, Seaman S, Hensiek A, Yeo T, Geans J, Compston A: No ecidence for a significant role of CTLA-4 in multiple sclerosis. J Neuroimmunol 2006, 171 ( 1-2); 193 – 197

Roxburgh RH, Seaman SR, Mastermann T, Hensiek AE, Sawcer SJ, Vukusic S, Achiti I, Confavreaux C, Coustans M, lePage E, Edan G, McDonnel GV, Hawkins S, Trojano M, Liguri M, Cocco E, Marrosu MG, Teser F, Leone MA, Weber A, Zipp F, Miterski B, Epplen JT, Oturai A, Sorensen PS, Celius EG, Lara NT, Montalban X, Villoslada P, Silva AM, Marta M, Leite I, Dubois B, Butzkueven H, Kilpatrick T, Mycko MP, Selmaj KW, Rio ME, Sa M, Salemi G, Hillert J, Compston DA. Multiple Sclerosis Severity Score: using disability and disease duration to rate severity. Neurology 2005; 64 (7): 1144 – 1151

Hensiek AE, Roxburgh R, Smilie B, Coraddu F, Akesson E, Holman P, Sawcer SJ, Compston DAS. Updated results of the United Kingdom linkage based genome screen in multiple sclerosis. J Neuroimmunol 2003, 143 (1-2): 25 – 30

Åkesson E, Coraddu F, Marrosu M, Massacesi L, Hensiek A, Harbo HF, Oturai A, Trojano M, Momigliano-Richiardi P, Cocco E, Murru R, Hillert J, Compston DAS, Sawcer SJ. Refining the linkage analysis on chromosome 10 in 449 sib-pairs with multiple sclerosis. J Neuroimmunol 2003; 143 (1-2): 31- 38

Yeo TW, Roxburgh R, Maranian M, Singlehurst S, Gray J, Hensiek A, Setakis E, Compston A, Sawcer S. Refining the analysis of a whole genome linkage disequilibrium association map: the United Kingdom. J Neuroimmunol 2003,; 143 (1-1): 53 – 59

Weber A, Infante-Duarte C, Sawcer S, Setakis E, Bellmann-Strobl J, Hensiek A, Rueckert S, Schoenemann C, Benediktsson K, Compston DAS, Zipp F. A genome-wide German screen for linkage disequilibrium in multiple sclerosis. J Neuroimmunol 2003, 143 (1-2): 79 – 83

Eraksoy M*, Hensiek A*, Kürtüncü M, Akman-Demir G, Kılınc M, Gedizlioglu M, Petek-Balcı B, Anlar O, Kutlu C, Saruhan-Direskeneli G, İdrisoglu HA, Setakis E, Compston A, Sawcer S & The Turkish Multiple Sclerosis Genetics Study Group. A genome screen for linkage disequilibrium in Turkish multiple sclerosis. J Neuroimmunol 2003, 143 (1-2): 129 – 132

Hensiek AE, Roxburgh R, Meranian M, Seaman S, Yeo T, Compston DA, Sawcer SJ : Osteopontin gene and clinical severity of multiple sclerosis. J Neurol 2003, 250(8):943-7

Hensiek AE, Compston DA, Sawcer SJ : Searching for needles in haystacks-the genetics of multiple sclerosis and other common neurological diseases. Brain Res Bull. 2003; 15;61(3):229-34.

Sawcer S, Maranian M, Hensiek A, Roxburgh R, Gray J, Compston A.: Crohn’s associated NOD2 gene variants are not involved in determining susceptibility to multiple sclerosis. J Neurol Neurosurg Psychiatry 2003; 74 (8): 1157

Hensiek AE, Sawcer SJ, Feakes R, Deans J, Mander A, Akesson E, Roxburgh R, Coraddu F, Smith S, Compston DA.: HLA-DR 15 is associated with female sex and younger age at diagnosis in multiple sclerosis.. J Neurol Neurosurg Psychiatry. 2002;72 (2):184-7

Sawcer S, l Maranian M, Setakis E, Val Curwen V, Akesson E, Hensiek A, Coraddu F, Roxburgh R, Sawcer D, Gray J, Deans J, Goodfellow PN, Walker N, Clayton D, Compston A.: A whole genome screen for linkage disequilibrium in multiple sclerosis confirms disease associations with regions previously linked to susceptibility. Brain 2002, 125: 1337 – 1347

Hensiek AE, Trimble MR. Relevance of new psychotropic drugs for the neurologist. J Neurol Neurosurg Psychiatry. 2002 ;72(3):281-5.

Coraddu F, Sawcer S, D’Alfonso S, Lai M, Hensiek A, Solla E, Broadley S, Mancosu C, Pugliatti M, Marrosu MG, Compston A.: A genome screen for multiple sclerosis in Sardinian multiplex families. Eur J Hum Genet. 2001;9 (8):621-6

Broadley S, Sawcer S, D’Alfonso S, Span>Hensiek A, Coraddu F, Gray J, Roxburgh R, Clayton D, Buttinelli C, Quattrone A, Trojano M, Massacesi L, Compston A. A genome screen for multiple sclerosis in Italian families. Genes Immun. 2001 Jun;2(4):205-10

Hensiek AE, Kellerman AJ, Hill JT.: Spontaneous regression of a solitary cerebral metastases in renal carcinoma and meningioma development under Medroxyprogesterone Acetate therapy . Br J Neurosurg 2000; 14 (4): 354 – 356